How to make a field mandatory using business rules

Summary:

I am working on a custom object, based on value of a field, i want to make another field mandatory. Is this possible using Business Rules

Content (required):

I am able to achieve this functionality using Workspace rules. But i want to implement this using business rules so that this condition also applies to people using the rest API.

However, i am only able to set value of a field based on a condition using Business rules and not do any other manipulation. Is this possible?

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