[oradev@testebs etc]$ isql -v thirchyroad
[S1000][unixODBC][Microsoft][SQL Server Native Client 11.0]Cannot generate SSPI context
[S1000][unixODBC][Microsoft][SQL Server Native Client 11.0]SSPI Provider: No credentials cache found
[ISQL]ERROR: Could not SQLConnect
I realise you have a few threads opened but this one does not involve any Oracle software so you should really follow up with Microsoft to see why their driver won't work with ISQL.
You could post your odbc.ini file here and we may be able to help but it looks like it is a problem with the driver setup or configuration.
Dharma the ODBC driver in question is not working probably because you have configured it to have an [Easysoft ODBC-SQL Server|http://www.easysoft.com/products/data_access/odbc-sql-server-driver/index.html] data source and you are using the Microsoft ODBC-SQL Server driver.