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Pl post exact OS version and the complete error message. Are you trying an in-place install/upgrade (i.e. in the same ORACLE_HOME) ? An out-of-place install/upgrade is recommended.
Important Changes to Oracle Database Patch Sets Starting With 188.8.131.52 [ID 1189783.1]
Complete checklist for out-of-place manual upgrade from previous 11.2.0.N version to the latest 11.2.0.N patchset. [ID 1276368.1]
These 2 are indeed 2 different OORACLE_HOME for oracle and hence care should be taken when setting up ORACLE_HOME. You might end up starting same database twice on Unix if you set the above 2 ORACLE_HOME and try starting same DB from each of these ORACLE_HOME.