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Login to database server and try to send mail from that server using telnet.
See this link
for more info
If this is working fine then problem is with Oracle. By default Network services are disabled on Oracle 11g so you need to create ACL for it. See this link for more info
Or search "Configure APEX mail in Oracle 11g" in google :)
Edited by: Hari_639 on May 8, 2010 12:12 AM