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I can think of two potential reasons why this error might come up. The first is that your WebLogic Cluster might be failing so that JNDI name-space replication between cluster servers has at least partially stopped working. The second is that you're working with multiple domains but there are duplicated names configured between domains. For the former, look for Warnings in your logs and also consult the general documentation for cluster troubleshooting information. As for the latter, consult the best practices section of the JMS configuration guide.