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SQL Developer doesn's provide this.
You can request it as an enhancement in the SQL Developer exchange (link at the top of the forum)
We've kicked around the idea of doing this for awhile. I believe there's already an item in the Exchange if you want to up vote it. The challenge being if it's a result set which hasn't been fully fetched, doing an aggregate would require one - and that could be costly. Of course folks live in the grids so I see the value in this type of feature as well.
As a workaround, you could of course export your data to CSV or XLS and do the calculations in your favorite spreadsheet software.