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You should try remove below lines and serve static content from Apache not from DB
Unload all modules from Apache you do not use.
ProxyPass /i http://backend-db:8080/i ProxyPassReverse /i http://backend-db:8080/i
It is hard give any good advice without full details about environment.
What is e.g. database version and edition?
What is APEX version?
What is Apache version?
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these documents should help you tune the shared server configuration:
Typically, serving static content via Apacha (as Jari mentioned) and some tweaks of the shared server parameters give quite acceptable performance if the load is not too heavy. However, you should investigate switching to Apex Listener or OHS / mod_plsql, if security and scaling is an issue.