Is this a fresh ADI setup and since then you are facing this issue? Please perform a step by step check on your ADI configuration.
Please refer link and double check all the steps:
did you ever solve this I am having the same issue with some of my Oracle ADI users as soon as they reboot the database settings are gone and greyed and you have to reinstall to fix until the next time they reboot then they disappear again.
Any help would be Appriciated.
We had to rebuild the users machine in the end and then it appeared to work. The IT Suppport team here said that it was a mixture of group policies and setting we changed to get Oracle ADI working on a windows 7 machine.
They disabled the group policies for the user after the re-build, installed Oracle ADI as the first instance and it worked. In my opinion if possible try loading Oracle ADI first before anything else goes down on the machine.