In the given scenario, you need to create 2 similar responsibilities and enable the personalisation for one.
Then assign the responsibilities to users accordingly.
In that case I would suggest you to handle it by a profile option:
- Setup custom profile, e.g. XX_PERSONALIZATION_ENABLED_PRF, values Yes/No
- Setup profile value to Yes at site level, but to No at specific user level.
- In condition of the personalization set something like:
fnd_profile.value('XX_PERSONALIZATION_ENABLED_PRF') = 'Y'
This way, in the future, you will be able to disable personalization for any other user simply by setting profile option for the user, without changing the personalization itself.