No. R12 is only certified on Oracle, Red Hat, and Suse Linux Enterprise Server.
Oracle E-Business Suite Installation and Upgrade Notes Release 12 (12.2) for Linux x86-64 (Doc ID 1330701.1)
Oracle E-Business Suite Installation and Upgrade Notes Release 12 (12.1.1) for Linux x86-64 (Doc ID 761566.1)
If you can get the exact same packages to install as required for Red Hat, it may work, but will not be considered certified or supported.
I just saw some client runing their PROD EBS 12.0.6 on cent OS 5.8.
Is it becuase cent OS is free open source?
Oracle Enterprise Linux supports costs are so low, I don't know why anyone would choose to run R12 on any other release, especially not am unsupported version.
Hmmm maybe it is out of ignorance?