From a database point of view, here's an extract from the documentation
Note: Starting with Oracle Database 11g Release 2 (22.214.171.124), Oracle Database supports Windows Server 2012 x64 and Windows Server 2012 R2 x64 on the Standard, Datacenter, Essentials, and Foundation editions. Windows Server 2012 R2 x64 requires Windows Database bundle patch 126.96.36.199.14 or higher.
Unfortunately I can't comment on Agile certification. If you have a MOS account, check the certification matrix there.
Hope this helps