ur requirement is not clear.
You are asking EBS related question in wrong forum. Kindly post under EBS
do the forms personalisation and in the condition context set level responsibility for all 100
add a condition to the forms personalisation that validate a cutom profile value and assign that profile to the 100 responsibility
there is no magic
hal9000akilroy 's approach will work.
Another thing you could do is include the logic in the Condition.
So the condition includes responsibility_id in <logic to select responsibilities> or responsibility_name like <criteria>
or for a more specific example, fnd_global.resp_name in (select responsibility_name from fnd_responsibility_tl where application_id = 101 or responsibility_name like '%ABC%')