Single Item buying from multiple sources

Dear Experts,

I have a below business case.

One operating Unit OU_DC has two inventory Organization (ORG1 and ORG2).

Inventory Item Code ‘A100’ is "Use Approved Supplier" enable. Organization ORG1 normally buy this item from Supplier No 100. User booked the quotation no 1000.  He has created the ASL entry, sourcing rule and assigned the sourcing rule to Supplier 100. Now while booking the PO, the system is defaulting the Unit price from Quotation 1000.

Same time ORG2 buy this item from Supplier No. 200. The packing (UOM) is different so there is a change unit price.

Before creating the new PO to buy the item for ORG2, user make the changes in ASL, Sourcing Rule and Assignment of Sourcing Rule.