Does the sensitivity of an excel file matter for a request load?

Hello, I downloaded 2 identical Company Maintenance files out of EDMCS. One of the excel files was marked with a sensitivity of Internal and the other was marked with a sensitivity of confidential (By default they are internal when downloaded, but a user set their copy to confidential). The file marked with Internal sensitivity will upload without issue. However, the file marked with confidential sensitivity will not upload. The only difference I note between the files is the sensitivity. Do you think this could be the issue?