Known issues with scheduling "Employee Vacation and Delegation Rules Report"?

We're looking to automate the "Employee Vacation and Delegation Rules Report," but the documentation recommends against scheduling it recurrently (only running it on an "as-needed" basis).

Has anyone encountered performance issues, data volume problems, or system instability when trying to run this report on a daily/weekly schedule? We're trying to figure out the specific risks before moving forward with a recurring schedule.