What is the best practice to route transfer orders to WMS and OTM cloud applications

We have majority of the transfers order created from replenishment Planning and some are created using SSP requisitions which should be integrated with WMS and OTM cloud for shipments. We have couple of large warehouses and small area distribution centres , smaller distrubution centres replenish from these larger warehouses . We have replenishment planning module in scope which creates majority of the transfer orders to the small branches.

Transfer order shipments are handled in WMS cloud and OTM is used for shipment planning.

Seek inputs on what should be the best practice ( Like routing transfer orders from OM or Inventory cloud) to WMS and OTM cloud keeping in view majority of the transfer orders created from replenishment planning.).