Create Miscellaneous Transaction Line, functionality of field queries

Summary:

The fields I have been asked to look at are the 'Location', 'Requester' and 'Reference' fields under the 'Create Miscellaneous Transaction' screen: 

What I have found out so far is: 

• For 'Location' you need to select either 'Internal' or 'External' in the 'Location Type' field, by selecting 'Internal' you can select any location (which is what we want), however by doing this will it drive any unintended functionality?
• It's the same question for the 'Requester' field, we can select all active users , but again does this drive any unintended functionality?

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