POR: Approved Pricing Only - How to set differently for different OUs?

 Hello,

Anybody aware of how to use the profile "POR: Approved Pricing Only" in a multi-org environment in 11.5.10?
This profile cannot be set at Responsibility level.

I need to set Approved pricing for one operating unit, and do not want to set it for another OU.

i.e, in one OU, we want only those items associated with a quotation or blanket to be extracted and visible for selection in iProcurement.

In the other OU, we want the item master item to be extracted and visible for selection in iProcurement, even if its not associated with a catalog quotation or Blanket agreement.