Item_ID/Location_ID combos in Sales_Data not in MDP_Matrix

Hi -

We are having data issues in worksheets and reporting and we found that there are numerous Item_ID/Location_ID combinations in Sales_Data table that do not exist in the MDP_Matrix table.  We think this is the cause of the data issues.  Is there a mechanism or script available that can syncronize these combinations?

Is this something that can be fixed by running MDP_ADD or EP_LOAD_MDP_LEVEL  or both?

Thanks