Movement of Objects from SYSTEM tablespace to USERS tablespace

Hello, 

I'm using Oracle 11.2.0.3 database and I have below doubt.

Can I move schema from one tablespace (SYSTEM) to another tablespace (USERS) within same database while the application is up and running.

Will there be any impact if I move the objects (tables & indexes) while the application is running.

Cmds used:

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alter table <table Name> move tablespace <new tablespace>;

alter index <Index Name> rebuild tablespace <New Tablespace>;

Thanks much,