Patches 13434486 and 6741280 - Failed With "Could not Connect to Server" Errors

Hello Support,
adpatch failed with : Unable to get the database connection using schema username/passwordIo exception: Connection refused(DESCRIPTION=(TMP=)(VSNNUM=186647296)(ERR=12514)(ERROR_STACK=(ERROR=
(CODE=12514)(EMFI=4))))

Below content is from adworker log file.  

Evaluating symbolic arguments ..
Net8 name-value connect string is:
(DESCRIPTION=(ADDRESS=(PROTOCOL=tcp)(HOST=usa0300uv1797.apps.mc.xerox.com)(PORT=1521))(CONNECT_DATA=(SERVICE_NAME=pnpp)(INSTANCE_NAME=pnpp04)(CID=(PROGRAM=)(HOST=usa030
0ux490)(USER=oraapps))))

DB Address is:
(ADDRESS=(PROTOCOL=tcp)(HOST=usa0300uv1797.apps.mc.xerox.com)(PORT=1521))

CONNECT_DATA is:
(CONNECT_DATA=(SERVICE_NAME=pnpp)(INSTANCE_NAME=pnpp04)(CID=(PROGRAM=)(HOST=usa0300ux490)(USER=oraapps)))