Recommendation on the next possible Primavera´s Deployment??? and how to implement . . .

Recommendation on the next possible Primavera´s Deployment??? and how to have a good implement . . . and Please I had read Primavera Sizing and tested config I need something more specific.

More than 100 users

Users will connect on P6 Professional Client, P6 Web.

More than 1000 Projects.

More than 5 regions around the country that will connect to my Primavera´s servers.

More than 5 regions with different kind of connections (optical fiber, frame relay, Satelital connection, Radio Connection, ADSL connection . . .)

Servers

1-

-Database servers.

An exlcusive instance to Primavera´s database???  An exclusive or dedicated server to Primavera's database???? Or can be a hugh server with multiple instances and one instance to Primavera´s database???