Restricting access by Inventory Organization using RBAC

Hello,

How can I achieve following using RBAC. This is on r12.1.3 Any Idea?

Scenario & Requirement

1. Using MOAC A responsibility is enabled for Inventory Organizations  ABC and DEF.

2. Now users can see ABC and  DEF related data using that information.

3. Requirement is users of ABC can not change or update data from DEF and vice versa when they are using same responsibility.

How can I implement above using RBAC?

Thanks,

Darsh