setup a bidirectional replication that includes Sequences

i need to setup a bidirectional replication that includes both DML&DDL ,in it need to replicate sequences i know  that its not supported in bi-directional and to overcome it I will need to create odd values at node and even on other node but that is not applicant for since there is  a dozen of sequences that will be recreated  thus if I excluded the sequence from being replicated from both sides will that effect data consistency ?? and what if a sequence is a part of a primary key ?

Thanks ,

Amira@