Content Zone for iProcurement be restricted based on Responsibility

I am trying to create a content zone for iProcurement and it should be secured by a responsibility. I have assigned a MO : Security profile for that responsibility and still when I select the responsibility, in the content zone I am not able to see the MO : Security profile.

My requirement is to restrict the items which is assigned to a particular inventory organization.

1. I have created a security profile for one inventory organization

2. Attached the security profile to the responsibility that I have created.