Is it possible to make an Inventory Location always "On Hold"?

Is there a way to set up an Inventory location to always be "on hold"?  Right now we set up the Inventory Locations in P4100 and if we want anything to show as not available we have to utilize the Lot Status code field when the inventory is put in the location.  Is there a way to make it so that anything in a certain location will always show unavailable but then show as Available when it's transferred out?  We are manufacturing product and sometimes putting it in a location that we don't want to show as available, but we