Adding new prefix in sca.config, will slee restart require to make change effective

Hi Team,

We have to add new prefix in sca.config file in SLC and we need to know whether slee restart require or we just edit the file and save the file with new changes and it will be effective? Or any other method please let us know.

Path: /IN/service_packages/SCA/etc/sca.config

{ prefix = "1002631637099" , remove_chars = "5" , add_chars = "" }