Can I use the "Create Credit Card Issuer Invoice" process without using the iExpense module ?

EBS Payables 12.2.11

We are moving off iExpense and implementing Concur Travel.

We are setting up a new corporate travel card to use with Concur, and my question is if I can set up that new card program in Payables and then continue to use the process of "Create Credit Card Issuer Invoice" to pay US Bank for the credit card transactions, but NOT use iExpense to do the "claim" portion and use up those credit card transactions?

And if the answer is yes, wondering if anyone has insight on what the reconciliation looks like since with iExpense, those credit card transactions sit in a balance sheet account until we use them on an expense report, that gets approved, and then lobbed over the fence of iExpense and imported into Payables as a payable invoice (which we do a zero dollar payment to clear out).