Need to know if we define 15+ custom processing constraints will it affect system performance

There is business requirement to define 15+ custom processing constraints.

1. If we define these number of constraints will it result into system performance issues?
2. Will it affect the performance of outbound integrations with external systems?
3. As per Oracle's recommendation, what is the maximum number of custom processing constraints that should be configured?
4. What should be the ideal sales order volume to handle these number of constraints?