AP Invoice approval - Spreadsheet setups for system holds

Summary:

PO AP Invoice has price and Qty variances and we want make use of AP Invoice approval using spreadsheet option to generate the workflow at line level which has system hold

Content (please ensure you mask any confidential information):

A. Is it possible to have line level approval for system holds such a Price and Qty variances in AP Invoice workflow if yes, can we have separate notification sent at each line level having system hold.

also

B. In case we can use a line-level approval - lets assume the invoice has 5 lines with a variance. Does the standard AP gives an option to the user to approve some lines (e.g. he approves 3), but reject the other lines (he rejects 2 lines