PO approval by ship-to Org

Summary:

Can PO approval be modified from default behavior based on certain conditions (for instance ship-to org)?

Content (required):

We use employee-supervisor hierarchy for approvals. Based on ship-to org, can we modify the default supervisor hierarchy? Vacation rules do not have the attribute ship-to org. We are looking at a way to reroute the approvals only for a specific ship-to org. If the default hierarchy is A->B->C->D, we would like to change it to A->B->X->Y. From C, it should be rerouted to X and follow X's employee hierarchy from there on.

Version (include the version you are using, if applicable):