Tools 8.5 upgrade: User Profile Processing Please wait when tab through various fields - PORTAL re

 I am upgrading HRMS from tools 8.46 to tools 8.50 on SQL Server 2008.  After the upgrade, when I try to change an employee's password through Security > User Profiles, the processing icon shows when I tab out of the Confirm Password field, and the system hangs until it times out.  A trace shows nothing is happening.  The system also hangs when I uncheck the Password Expired field.  It also hangs if I just tab through the fields of Permission Lists at the bottom of the page for the fields with prompt tables.

We do have the portals set up, which is the only difference between our dev environment from our demo environment.  I do not have this problem in our demo environment.