Please help me diagnose workflow issues!

 Dears,I encounter the following error, please help me diagnose.

To  SYSADMIN 

Sent  2012-09-25 11:07:03 

ID  63303 

An Error occurred in the following Workflow.

Item Type = POAPPRV

Item Key = 12670-16722

User Key =159

Error Name = WF_ERROR

Error Message = [WF_ERROR] ERROR_MESSAGE=3835: 在为事件 'oracle.apps.wf.notification.send' 执行生成功能 'WF_XML.Generate' 的过程中遇到错误 '-20001 - ORA-20001: Oracle 错误 -6508：fnd_global.set_nls 中检测到 ORA-04061: package "APPS.FND_PROFILE" 的当前状态失效

ORA-04065: 未执行, 已变更或删除 package "APPS.FND_PROFILE"

ORA-06508: PL/SQL: 无法找到正在调用 : "APPS.FND_PROFILE" 的程序单元

ORA-04061: package "APPS.FND_PROFILE" 的当前状态失效

ORA-04065: 未执行, 已变更或删除 package "APPS.FND_PROFILE"

ORA-06508: PL/SQL: 无法找到正在调用 : "APPS.FND_PROFILE" 的程序单元

。' 。 ERROR_STACK=

Wfa_Sec.Get_Role_Info2(CAIRONG.LI)