Can you have different due to/due from for interunit accounting based on business unit/account combi

I've read the peoplebooks on interunit processing but i'm having a hard time understanding it. I basically want to know if you can setup different due to/due from accounitng based not only on business unit to business unit but a combination of business unit and account. So it would be something like Business unit 1 with account 6xxxxxx and affilate 2 would have a due to/from account of 1234567 and Business unit 1 with account 4xxxxxx and affilate 2 would have a due to/from account of 7654321. Is this possible?

Thanks

Mike