Is there a way to disable active GL accounts in the subsystems?

The issue that prompted this question, is there a way to disable accounts in the subsystems even though they are still active in the main General Ledger System? The subsystems (AP & eProcurement) are allowing users to post entries in the GL system. The reason we want to do this is to prevent users from posting expense transactions to revenue accounts. However, we still want them to be able to use the subsystems for other purposes. Can this be done? If so, how?