Can we deploy multiple instances of the same visual application to one VB runtime instance?

Summary:

Is there a way to deploy multiple instances of the same visual application to one VB runtime instance?

Content (required):

Our application is targeting multiple organisational units, each having their own separate data-storage (database schemas) and rest service endpoints. The structure of these database schemas and rest services is homogeneous across the units, so all will fit the same visual application. We expect to end up using both business objects and rest services as backend to the application.

We are investigating a way to make our application switch the rest endpoints and the database schema for the business objects dynamically, based on the organisational unit the current user belongs to.